Cloverleaf is a census-designated place (CDP) in east central Harris County, Texas, United States. Cloverleaf originated as a stop on the Beaumont, Sour Lake and Western Railway. A 1936 county highway map indicates an unnamed development which became Cloverleaf. The Handbook of Texas states that a post office may have existed for a short period of time around 1950. Cloverleaf is zoned to schools in the Galena Park Independent School District.